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IgG3 Fc

概要

Name:Immunoglobulin G
Target Synonym:Immunoglobulin G
Number of Launched Drugs:1
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Approved

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製造番号 種類 製品説明 構造 純度 特徴
IG3-M5214 Mouse Mouse IgG3 Fc Protein, Tag Free (MALS verified)
IG3-M5214-structure
IG3-M5214-sds
IG3-H5200 Human Human IgG3 Fc Protein, Tag Free (MALS & SPR verified)
IG3-H5200-structure
IG3-H5200-sds
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生物活性データの一部

IG3-H5200-SPR
Human_FcRn_Heterodimer_Protein_SPR

Human FCGRT&B2M Heterodimer Protein, His Tag (Cat. No. FCN-H52W7) captured on CM5 Chip via anti-His antibody can bind Human IgG3 Fc, Tag Free (Cat. No. IG3-H5200) with an affinity constant of 2.82 μM as determined in SPR assay (Biacore 8K) (QC tested).

IG3-M5214-MALS-HPLC
Mouse IgG3 Fc Protein, Tag Free (Cat. No. ) MALS images

The purity of Mouse IgG3 Fc Protein, Tag Free (Cat. No. IG3-M5214) is more than 90% and the molecular weight of this protein is around 60-70 kDa verified by SEC-MALS.

Bioactivity-ELISA
Mouse IgG3 Fc Protein, Tag FreeMouse IgG3 Fc Protein, Tag Free (Cat. No. IG3-M5214) ELISA bioactivity

Immobilized Mouse IgG3 Fc Protein, Tag Free (Cat. No. IG3-M5214) at 5 μg/mL (100 μL/well) can bind Biotinylated Human CD64, His,Avitag (Cat. No. FCA-H82E8) with a linear range of 0.6-10 ng/mL (QC tested).

Synonym Name

Ig gamma-3 chain C region,IgG, IgG3

Background

Immunoglobulin G3 (IgG3) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-3 chain C region (IgG3-Fc / IGHG3) contains two constant regions of IgG3 H chain (CH2, CH3).

Clinical and Translational Updates

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